Biological correlates of prostate cancer perineural invasion diameter
نویسندگان
چکیده
منابع مشابه
Perineural Invasion and Risk of Lethal Prostate Cancer.
Background: Prostate cancer has a propensity to invade and grow along nerves, a phenomenon called perineural invasion (PNI). Recent studies suggest that the presence of PNI in prostate cancer has been associated with cancer aggressiveness.Methods: We investigated the association between PNI and lethal prostate cancer in untreated and treated prostate cancer cohorts: the Swedish Watchful Waiting...
متن کامل[Prognostic role of perineural invasion in prostate biopsy].
INTRODUCTION Despite tumour cell dissemination through the intraprostatic nervous system being considered as a prostate cancer progression mechanism, the significance of perineural invasion in prostate biopsies to predict extraprostatic extension and its use as a potential prognosis factor is controversial. MATERIALS AND METHODS Retrospective study carried out at an institution on 208 patient...
متن کاملDoes perineural invasion on prostate biopsy predict adverse prostatectomy outcomes?
OBJECTIVE To determine the relationship between perineural invasion (PNI) on prostate biopsy and radical prostatectomy (RP) outcomes in a contemporary RP series, as there is conflicting evidence on the prognostic significance of PNI in prostate needle biopsy specimens. PATIENTS AND METHODS From 2002 to 2007, 1256 men had RP by one surgeon. Multivariable logistic regression and Cox proportiona...
متن کاملperineural invasion on prostate biopsy predict adverse prostatectomy outcomes ?
control peritoneal fluid and bowel edema. In the critically injured Urology patients, the “VAC PAC” should be more liberally used. The use of damage control in urology mainly applies to the injured ureter, where the ureter can either be ligated, or a pediatric feeding tube or ureteral stent placed up the cut ureteral edge and the stent pulled quickly through the skin. Here, definitive measures ...
متن کاملExpression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer.
BACKGROUND Perineural invasion (PNI) is the dominant pathway for local invasion in prostate cancer. To date, only few studies have investigated the molecular differences between prostate tumors with PNI and those without it. METHODS To evaluate the involvement of both microRNAs and protein-coding genes in PNI, we determined their genome-wide expression with a custom microRNA microarray and Af...
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ژورنال
عنوان ژورنال: Human Pathology
سال: 2014
ISSN: 0046-8177
DOI: 10.1016/j.humpath.2014.02.011